Blar i forfatter "Acharya, Ganesh"

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    • The acceptability of implementing patient-reported measures in routine maternity care: A systematic review 

      Chen, An; Väyrynen, Kirsi; Leskelä, Riikka-Leena; Torkki, Paulus; Heinonen, Seppo; Tekay, Aydin; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-16)
      Introduction - Patient-reported measures (PRMs) are becoming popular as they might influence clinical decisions, help to deliver patient-centered care, and improve health care quality. However, the limited knowledge and consensus about the acceptability of implementing PRMs in maternity care hinder their widespread use in clinical practice, and evidence-based recommendations are lacking. This ...

    • Adverse events reporting by obstetric units in Norway as part of their quality assurance and patient safety work: an analysis of practice 

      Johansen, Lars Thomas; Braut, Geir Sverre; Acharya, Ganesh; Andresen, Jan Fredrik; Øian, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
      Background - The Norwegian Board of Health Supervision aims to contribute to the improvement of quality and patient safety in the healthcare services. Planned audits were performed to investigate how 12 selected Norwegian obstetric units reported and analyzed adverse events as the part of their quality assurance and patient safety work.<p> Methods - Serious adverse events coded as birth asphyxia, ...

    • Agreement between anatomical M-mode and tissue Doppler imaging in the assessment of fetal atrioventricular annular plane displacement in uncomplicated pregnancies: A prospective longitudinal study 

      Zanardini, Cristina; D'Antonio, Francesco; Hvingel, Bodil; Vårtun, Åse; Prefumo, Federico; Flacco, Maria E.; Manzoli, Lamberto; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-23)
      Aim To evaluate the level of agreement between M‐mode and pulsed‐wave tissue Doppler imaging (PW‐TDI) techniques in assessing fetal mitral annular plane systolic excursion (MAPSE), tricuspid annular plane systolic excursion (TAPSE) and septal annular plane systolic excursion (SAPSE) in a low‐risk population. Methods This prospective longitudinal study included healthy fetuses assessed from 18 to ...

    • Agreement between preload reserve measured by impedance cardiography and echocardiography during pregnancy 

      Liang, Huan; Vårtun, Åse; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-05)
      <i>Purpose</i>: Accurate assessment of cardiac function is important during pregnancy. Echocardiography and impedance cardiography (ICG) are commonly used noninvasive methods to measure stroke volume (SV) and cardiac output (CO). The diference in stroke volume (ΔSV) or cardiac output (ΔCO) measured at baseline and after passive leg raising (PLR) is a measure of preload reserve that predicts volume ...

    • Automated analysis of color tissue Doppler velocity recordings of the fetal myocardium using a new algorithm 

      Herling, Lotta; Johnson, Jonas; Ferm-Widlund, Kjerstin; Lindgren, Peter; Acharya, Ganesh; Westgren, Magnus (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-27)
      Background: Tissue Doppler imaging (TDI) can be used to assess fetal cardiac function and it has been shown to detect changes associated with hypoxia in animal models. However, the analysis is cumbersome and time consuming. The main objective of this study was to evaluate the feasibility of a new algorithm developed for the automated analysis of color TDI velocity recordings of the fetal myocardium. ...

    • Automated analysis of fetal cardiac function using color tissue Doppler imaging in second half of normal pregnancy 

      Herling, Lotta; Johnson, Jonas; Ferm-Widlund, Kjerstin; Bergholm, Fredrik; Elmstedt, Nina; Lindgren, Peter; Sonesson, Sven-Erik; Acharya, Ganesh; Westgren, Magnus (Journal article; Tidsskriftartikkel, 2018-02-26)
      <i>Objectives</i> - Color tissue Doppler imaging (cTDI) is a promising tool for the assessment of fetal cardiac function. However, the analysis of myocardial velocity traces is cumbersome and time‐consuming, limiting its application in clinical practice. The aim of this study was to evaluate fetal cardiac function during the second half of pregnancy and to develop reference ranges using an ...

    • China's community-based strategy of universal preconception care in rural areas at a population level using a novel risk classification system for stratifying couples´ preconception health status 

      Zhou, Qiongjie; Zhang, Shikun; Wang, Qiaomei; Shen, Haiping; Tian, Weidong; Chen, Jingqi; Acharya, Ganesh; Li, Xiaotian (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-28)
      <i>Background</i>: Preconception care (PCC) is recommended for optimizing a woman’s health prior to pregnancy to minimize the risk of adverse pregnancy and birth outcomes. We aimed to evaluate the impact of strategy and a novel risk classification model of China´s “National Preconception Health Care Project” (NPHCP) in identifying risk factors and stratifying couples’ preconception health ...

    • Chip-based multimodal super-resolution microscopy for histological investigations of cryopreserved tissue sections 

      Villegas, Luis; Dubey, Vishesh Kumar; Nystad, Mona; Tinguely, Jean-Claude; Coucheron, David Andre; Dullo, Firehun Tsige; Priyadarshi, Anish; Acuna Maldonado, Sebastian Andres; Ahmad, Azeem; Mateos, Jose M.; Barmettler, Gery; Ziegler, Urs; Birgisdottir, Åsa Birna; Hovd, Aud-Malin Karlsson; Fenton, Kristin Andreassen; Acharya, Ganesh; Agarwal, Krishna; Ahluwalia, Balpreet Singh (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-24)
      Histology involves the observation of structural features in tissues using a microscope. While diffraction-limited optical microscopes are commonly used in histological investigations, their resolving capabilities are insufficient to visualize details at subcellular level. Although a novel set of super-resolution optical microscopy techniques can fulfill the resolution demands in such cases, the ...

    • Coronary flow reserve in pregnant rats with increased left ventricular afterload 

      Songstad, Nils Thomas; Serrano, Maria; Sitras, Vasilis; Johansen, David; Ytrehus, Kirsti; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-07-09)
      Background Coronary flow reserve (CFR) is used as a measure of coronary endothelial function. We investigated the effect of increased afterload on CFR of pregnant and non-pregnant rats. Methods Afterload increase in Wister rats (both pregnant and non-pregnant) was achieved by the infusion of angiotensin II (Ang II) for ~10 days or by subjecting them to transverse aortic constriction (TAC) ...

    • Dental caries and preterm birth: a systematic review and meta-analysis 

      Wagle, Madhu; D'Antonio, Francesco; Reierth, Eirik; Basnet, Purusotam; Trovik, Tordis A; Orsini, Giovanna; Manzoli, Lamberto; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-02)
      Objectives:<br> The primary objective of this systematic review was to evaluate the association between dental caries and preterm birth (PTB). The secondary objective was ascertaining the difference between women with dental caries who experienced PTB and those who did not with regard to decayed, missing and filled teeth (DMFT), and decayed, missing and filled surfaces (DMFS) indices. <br>M ...

    • Differences in gene expression between first and third trimester human placenta : a microarray study. 

      Sitras, Vasilis; Fenton, Christopher Graham; Paulssen, Ruth H; Vårtun, Åse; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The human placenta is a rapidly developing organ that undergoes structural and functional changes throughout the pregnancy. Our objectives were to investigate the differences in global gene expression profile, the expression of imprinted genes and the effect of smoking in first and third trimester normal human placentas. Placental samples were collected from 21 women with uncomplicated pregnancies ...

    • Divergent Regulation of Decidual Oxidative-Stress Response by NRF2 and KEAP1 in Preeclampsia with and without Fetal Growth Restriction 

      Mundal, Siv Boon; Rakner, Johanne Johnsen; Silva, Gabriela; Gierman, Lobke; Austdal, Marie; Basnet, Purusotam; Elschot, Mattijs; Bakke, Siril Skaret; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Moses, Eric; Acharya, Ganesh; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-10)
      Utero-placental development in pregnancy depends on direct maternal–fetal interaction in the uterine wall decidua. Abnormal uterine vascular remodeling preceding placental oxidative stress and placental dysfunction are associated with preeclampsia and fetal growth restriction (FGR). Oxidative stress is counteracted by antioxidants and oxidative repair mechanisms regulated by the transcription factor ...

    • Do dentists have better oral health compared to general population: A study on oral health status and oral health behavior in Kathmandu, Nepal 

      Wagle, Madhu; Trovik, Tordis A; Basnet, Purusotam; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Effect of Angiotensin II on the Left Ventricular Function in a Near-Term Fetal Sheep with Metabolic Acidemia 

      Acharya, Ganesh; Huhta, James; How, Ole-Jakob (Journal article; Tidsskriftartikkel, 2011)

    • Effect of cigarette smoking on serum anti-Mullerian hormone and antral follicle count in women seeking fertility treatment: a prospective cross-sectional study 

      Bhide, Priya; Timlick, Elizabeth; Kulkarni, Abhijit; Gudi, Anil; Shah, Amit; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-31)
      Objectives The relationship between smoking and ovarian reserve markers is inconclusive. The primary objective of our study was to assess the effect of cigarette smoking on the quantitative ovarian reserve parameters, serum anti-Mullerian hormone (AMH) and antral follicle count (AFC) as relevant to prediction of fertility outcomes in women seeking fertility treatment. Our secondary aims were ...

    • Effect of Passive Leg Raising on Systemic Hemodynamics of Pregnant Women: A Dynamic Assessment of Maternal Cardiovascular Function at 22–24 Weeks of Gestation 

      Vårtun, Åse; Flo, Kari; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Effect of Transverse Aortic Constriction on Cardiac Structure, Function and Gene Expression in Pregnant Rats 

      Songstad, Nils Thomas; Johansen, David; How, Ole-Jakob; Kaaresen, Per Ivar; Ytrehus, Kirsti; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      Background: There is an increased risk of heart failure and pulmonary edema in pregnancies complicated by hypertensive disorders. However, in a previous study we found that pregnancy protects against fibrosis and preserves angiogenesis in a rat model of angiotensin II induced cardiac hypertrophy. In this study we test the hypothesis that pregnancy protects against negative effects of increased ...

    • Effectiveness, safety and acceptability of self-assessment of the outcome of first-trimester medical abortion: a systematic review and meta-analysis 

      Baiju, Nikita; Acharya, Ganesh; D'Antonio, Francesco; Berg, Rigmor (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-31)
      <i>Background</i> - For many women, the need for multiple clinical visits is a barrier to medical abortion.<p> <p><i>Objectives</i> - We assessed the effectiveness, safety, and acceptability of self‐assessment of the outcome of medical abortion completed at home versus routine clinic follow up after medical abortion.<p> <p><i>Search strategy</i> - We searched databases such as MEDLINE, Embase, ...

    • Effects of high intensity interval training on pregnant rats, and the placenta, heart and liver of their fetuses. 

      Songstad, Nils Thomas; Kaspersen, Knut-Helge; Hafstad, Anne Dragøy; Basnet, Purusotam; Ytrehus, Kirsti; Acharya, Ganesh (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-13)
      Objective To investigate the effects of high intensity interval training (HIIT) on the maternal heart, fetuses and placentas of pregnant rats. <p>Methods Female Sprague-Dawley rats were randomly assigned to HIIT or sedentary control groups. The HIIT group was trained for 6 weeks with 10 bouts of high intensity uphill running on a treadmill for four minutes (at 85–90% of maximal oxygen consumption) ...

    • Effects of nifedipine and sildenafil on placental hemodynamics and gas exchange during fetal hypoxemia in a chronic sheep model 

      Alanne, Leena; Bhide, Amarnath; Hoffren, Jonna; Lantto, Juulia; Huhta, Heikki; Kokki, Merja; Haapsamo, Mervi; Acharya, Ganesh; Rasanen, Juha (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-16)
      Introduction - We hypothesized that nifedipine and sildenafil would have no detrimental effects on placental hemodynamics and gas exchange under fetal hypoxemia.<p> <p>Methods - In 33 chronically instrumented fetal sheep, placental volume blood flow (QPlac) and umbilical artery (UA) vascular impedance were measured by Doppler ultrasonography. Fetal carotid artery blood pressure and blood gas ...